TY - JOUR AB - Rapeseed meal (RSM) hydrolysate was evaluated as substitute for commercial nutrient supplements in 1,3-propanediol (PDO) fermentation using the strain Clostridium butyricum VPI 1718. RSM was enzymatically converted into a generic fermentation feedstock, enriched in amino acids, peptides and various micro-nutrients, using crude enzyme consortia produced via solid state fermentation by a fungal strain of Aspergillus oryzae. Initial free amino nitrogen concentration influenced PDO production in batch cultures. RSM hydrolysates were compared with commercial nutrient supplements regarding PDO production in fed-batch cultures carried out in a bench-scale bioreactor. The utilization of RSM hydrolysates in repeated batch cultivation resulted in a PDO concentration of 65.5 g/L with an overall productivity of 1.15 g/L/h that was almost 2 times higher than the productivity achieved when yeast extract was used as nutrient supplement. (C) 2014 Elsevier Ltd. All rights reserved. AD - Agr Univ Athens, Dept Food Sci & Human Nutr, GR-11855 Athens, Greece AN - WOS:000335393500023 AU - Chatzifragkou, A. AU - Papanikolaou, S. AU - Kopsahelis, N. AU - Kachrimanidou, V. AU - Dorado, M. P. AU - Koutinas, A. A. DA - May DO - 10.1016/j.biortech.2014.02.021 J2 - Bioresource Technol KW - biorefineries LA - English N1 - Ag4mh PY - 2014 SN - 0960-8524 SP - 167-175 ST - Biorefinery development through utilization of biodiesel industry by-products as sole fermentation feedstock for 1,3-propanediol production T2 - Bioresource Technology TI - Biorefinery development through utilization of biodiesel industry by-products as sole fermentation feedstock for 1,3-propanediol production UR - ://WOS:000335393500023 VL - 159 ID - 9796 ER -